Yes, that can be done with a Conditional Drop Down setup, sometimes called CDD.
Presumably you already have a table of Airports.
You will need a Table called say Airport Hotels similar to your attached CSV file, but with the Airport Code filled in for every record.
Then your form will pull in the hotel name from a relationship lookup from the Airport Hotels table.
On the field for Related Airport Hotel, you will go to the field properties and set the conditional checkbox, and set it so that once you select the airport code on your "Traveller" record, it will limit the Hotels choices to just the Airport Hotels for that Airport code on the Traveller record.